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Haplogroup Q-M3

Q-M3 (Primary Native American founding lineage)

Macro-haplogroup
Q
Parent clade
Q1a-MEH2
Formed (estimate)
c. 14,000–16,000 years before present
TMRCA (estimate)
c. 13,000–14,000 years ago

Overview

Q-M3 is the principal paternal founding lineage of Indigenous peoples across North, Central and South America. Emerging shortly after the divergence of ancestral Beringian populations, Q-M3 underwent an explosive expansion synchronized with the earliest successful settlement of the American continents. Archaeogenetic evidence shows that M3-derived lineages were present during both pre-Clovis and Clovis periods, and their descendants continue to dominate the Y-chromosome landscape of the Americas.

Geographic distribution

Q-M3 shows extremely high frequencies among Native American groups from Canada to Patagonia. It occurs in Algonquian, Iroquoian, Na-Dene, Andean, Mesoamerican and Amazonian populations. In modern Eurasia Q-M3 appears only at very low levels, often as back-migrations or isolated Siberian traces.

Ancient DNA

  • The Anzick-1 Clovis child (~12,600 BP) belonged to a Q-M3 downstream lineage, demonstrating deep antiquity.
  • Ancient genomes from both North and South America show continuity with Q-M3-related lineages over 10,000+ years.
  • The timing of M3 expansion matches the earliest widespread archaeological signatures of the initial human dispersal across the Americas.

Phylogeny & subclades

Q-M3 contains numerous downstream branches including Q-M848, Q-Y4300, Q-Y4276, Q-Z19400 and multiple Amazonian and Andean-specific clades. Its star-like branching pattern reflects rapid demographic growth during initial continental settlement.

  • Q-M848
  • Q-Y4300
  • Q-Y4276
  • Q-Z19400

Notes & context

Q-M3 is the dominant paternal lineage of Native American populations and a key marker for understanding early human migration into the Western Hemisphere.