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Haplogroup I3c

I3-Y18195

Macro-haplogroup
I
Parent clade
I3
Formed (estimate)
c. 20,000–25,000 years before present
TMRCA (estimate)
c. 12,000–14,000 years ago

Overview

I3c (Y18195) is a rare but phylogenetically informative branch of haplogroup I3 found primarily around the Caucasus–Zagros interaction zone. Its deep divergence time indicates survival of an isolated Upper Paleolithic paternal line that persisted through the climatic fluctuations of the Last Glacial Maximum. I3c likely represents groups inhabiting mountain foothills and highland refugia that connected the Caucasus, eastern Anatolia, and the Zagros corridor.

Geographic distribution

Modern occurrences are concentrated in northeastern Turkey, Armenia, western Iran and parts of the South Caucasus. Low frequencies have been detected in the Levant and occasionally in southeastern Europe, likely via ancient trans-Anatolian movements.

Ancient DNA

  • Indirect evidence appears in Upper Paleolithic genomic clusters from the Caucasus region, which show affinity for deep West Eurasian lineages.
  • Neolithic and Chalcolithic individuals from the Zagros highlands exhibit related basal branches within larger I-like signals, though explicit I3c assignment awaits higher Y coverage.
  • The lineage’s distribution suggests longstanding highland continuity through Holocene cultural transitions.

Phylogeny & subclades

I3c branches alongside I3a and I3b as one of the three major sublineages of I3. Y18195 and downstream SNPs define a tight cluster that reflects ancient isolation. Its slow diversification and geographic confinement contrast with the more complex radiations of I1 and I2.

  • I3-Y18407
  • I3-FGC5613
  • Basal I3c*

Notes & context

I3c provides a rare window into Upper Paleolithic paternal diversity in the highland Near East. Its presence in modern populations at low frequencies underscores how some deeply divergent West Eurasian lineages survived in ecological refugia far from major demographic pulses.